Structure of PDB 6n7p Chain I Binding Site BS04

Receptor Information

>6n7p Chain I (length=192) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MSTPAAEQRKLVEQLMGLHDPKICKSYLVGECPYDLFQGTKQSLGKCPQM
HLTKHKIQYEREVKQGKTFPEFEREYLAILSRFVNECNGQISVALQNLKH
TAEERMKIQQVTEELDVLDLISKRKEVAKRVRNITENVGQSAQQKLQVCE
VCGAYLSRLDTDRRLADHFLGKIHLGYVKMREDYDRLMKNNR

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6n7p Chain I Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6n7p A unified mechanism for intron and exon definition and back-splicing.
Resolution	3.6 Å
Binding residue (original residue number in PDB)	C201 C204 H220 H226
Binding residue (residue number reindexed from 1)	C149 C152 H168 H174
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003729	mRNA binding
GO:0008270	zinc ion binding

	Biological Process
GO:0000395	mRNA 5'-splice site recognition
GO:0000398	mRNA splicing, via spliceosome
GO:0006376	mRNA splice site recognition
GO:0006397	mRNA processing
GO:0008380	RNA splicing

	Cellular Component
GO:0000243	commitment complex
GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0005685	U1 snRNP
GO:0005829	cytosol
GO:0071004	U2-type prespliceosome

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Cellular Component

External links

PDB	RCSB:6n7p, PDBe:6n7p, PDBj:6n7p
PDBsum	6n7p
PubMed	31485080
UniProt	Q07508\|LUC7_YEAST Protein LUC7 (Gene Name=LUC7)

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