Structure of PDB 1de7 Chain H Binding Site BS04
Receptor Information
>1de7 Chain H (length=249) Species:
9606
(Homo sapiens) [
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IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPW
DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI
ALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQP
SVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGG
PFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ
Ligand information
>1de7 Chain B (length=10) [
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TVELQGVVPR
Receptor-Ligand Complex Structure
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PDB
1de7
Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
H57 S195
Binding residue
(residue number reindexed from 1)
H43 S198
Enzymatic activity
Enzyme Commision number
3.4.21.5
: thrombin.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
GO:0005509
calcium ion binding
Biological Process
GO:0006508
proteolysis
GO:0007596
blood coagulation
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Molecular Function
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Biological Process
External links
PDB
RCSB:1de7
,
PDBe:1de7
,
PDBj:1de7
PDBsum
1de7
PubMed
10956659
UniProt
P00734
|THRB_HUMAN Prothrombin (Gene Name=F2)
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