Structure of PDB 7c2g Chain G Binding Site BS04

Receptor Information
>7c2g Chain G (length=196) Species: 1706445 (Candidatus Thorarchaeota archaeon SMTZ1-83) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TEPTVFHIQKGRLVRMSDPGAFGRGDCYLVDAGPKIYLWIGPKSTADEKF
LTAASAVFKDTERKGHADIDRIEGGKEPEEFKVLFDDFQLTDEDTEGILR
RVQLEKREYKLWRVHHEGDDTFFAEVPLSRSSLRSDDVYLVDTWDDIFVW
RGKDASAREKFDGTMLARRYDAERVGVQEIELIEDGSEPEEFWRSF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7c2g Chain G Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7c2g Insights into the evolution of regulated actin dynamics via characterization of primitive gelsolin/cofilin proteins from Asgard archaea
Resolution1.71 Å
Binding residue
(original residue number in PDB)		D172 R175 G177 Q179
Binding residue
(residue number reindexed from 1)		D171 R174 G176 Q178
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0046872 metal ion binding
GO:0051015 actin filament binding
Biological Process
GO:0051014 actin filament severing
GO:0051016 barbed-end actin filament capping

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7c2g, PDBe:7c2g, PDBj:7c2g
PDBsum7c2g
PubMed
UniProtA0A135VHY8

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