Structure of PDB 3glg Chain G Binding Site BS04

Receptor Information

>3glg Chain G (length=378) Species: 83333 (Escherichia coli K-12)

GLEVLFQGPHMSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHA
YLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDL
IEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALL
KTLEEPPEHVKFLLATADPQKLPVTILSRCLQFHLKALDVEQIRHQLEHI
LNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM
LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLH
RIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLIGRKELP
YAPDRRMGVEMTLLRALAFHPRMPLPEP

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3glg Chain G Residue 415

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3glg The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
• Resolution: 3.25 Å
• Binding residue (original residue number in PDB): T52 D126
• Binding residue (residue number reindexed from 1): T62 D136
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003887 DNA-directed DNA polymerase activity
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006260 DNA replication

Cellular Component

• GO:0009360 DNA polymerase III complex

External links

• PDB: RCSB:3glg, PDBe:3glg, PDBj:3glg
• PDBsum: 3glg
• PubMed: 19450514
• UniProt: P06710|DPO3X_ECOLI DNA polymerase III subunit tau (Gene Name=dnaX)