Structure of PDB 1h1v Chain G Binding Site BS04

Receptor Information
>1h1v Chain G (length=327) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGQIIYN
WQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGK
PMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND
AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFW
EALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQED
LATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRT
PITVVKQGFEPPSFVGWFLGWDDDYWS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1h1v Chain G Residue 1746 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1h1v The Calcium Activation of Gelsolin:Insights from the 3A Structure of the G4-G6/Actin Complex
Resolution2.99 Å
Binding residue
(original residue number in PDB)		D669 D670 E692
Binding residue
(residue number reindexed from 1)		D254 D255 E277
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding

View graph for
Molecular Function
External links
PDB RCSB:1h1v, PDBe:1h1v, PDBj:1h1v
PDBsum1h1v
PubMed12460571
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN)

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