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Receptor Information

>8edg Chain E (length=550) Species: 7370 (Musca domestica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MDNLEVKAKINQGLYKITPRHKGTSFIWNVLADIQKEDDTLVEGWVFCRK
CEKVLKYTTRQTSNLCRHKCCASLKQSRELKTVSADCKKEAIEKCAQWVV
RDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTS
DAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNE
LRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANV
VKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANL
QHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHIN
KSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDV
ADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEF
CLSKMEDPVCPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLAL
SLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK

>8edg Chain R (length=55) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

caagtggcgcataagtatcaaaataagccacttgttgttgttctctggtt
cacgc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8edg Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Resolution	4.64 Å
Binding residue (original residue number in PDB)	N587 R588
Binding residue (residue number reindexed from 1)	N528 R529

Enzyme Commision number

	Molecular Function
GO:0003677	DNA binding
GO:0046872	metal ion binding
GO:0046983	protein dimerization activity

	Biological Process
GO:0006357	regulation of transcription by RNA polymerase II

	Cellular Component
GO:0005634	nucleus

PDB	RCSB:8edg, PDBe:8edg, PDBj:8edg
PDBsum	8edg
PubMed	37491363
UniProt	Q25438

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Structure of PDB 8edg Chain E Binding Site BS04