Structure of PDB 5yi3 Chain E Binding Site BS04

Receptor Information
>5yi3 Chain E (length=145) Species: 272623 (Lactococcus lactis subsp. lactis Il1403) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLANQIDQFLGTIMQFAENKHEILLGKSESDVKLTSTQEHILMLLAEQI
STNAKIAEKLKISPAAVTKALKKLQEQELIKSSRATNDERVVLWSLTEKA
VPVAKEHATHHEKTLSTYQELGNKFTDEEQEVISKFLSALTEEFQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5yi3 Chain E Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5yi3 Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		E24 H42 H108 H112
Binding residue
(residue number reindexed from 1)		E23 H41 H107 H111
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5yi3, PDBe:5yi3, PDBj:5yi3
PDBsum5yi3
PubMed29229866
UniProtQ9CDU5

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