Structure of PDB 4esv Chain E Binding Site BS04

Receptor Information
>4esv Chain E (length=418) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIEAEQAVLGAVFLDPAALVPASEILIPEDFYRAAHQKIFHAMLRVADRG
EPVDLVTVTAELAASEQLEEIGGVSYLSELADAVPTAANVEYYARIVEEK
SVLRRLIRTATSIAQDGYTREDEIDVLLDEADRKIMEGAFKNIKDILVQT
YDNIEMLHNITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNI
AQNVATKTNENVAIFSLEMSAQQLVMRMLCAEGNINAQNLRTGKLTPEDW
GKLTMAMGSLSNAGIYIDDTPSIRVSDIRAKCRRLKQESGLGMIVIDYLQ
LIQGSGRSKENRQQEVSEISRSLKALARELEVPVIALSQLSRSVEQRQDK
RPMMSDIRESGSIEQDADIVAFLYRDDYYNKDSENKNIIEIIIAKQRNGP
VGTVQLAFIKEYNKFVNL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4esv Chain E Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4esv The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		T217 D320
Binding residue
(residue number reindexed from 1)		T194 D297
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
Cellular Component
GO:0005829 cytosol
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4esv, PDBe:4esv, PDBj:4esv
PDBsum4esv
PubMed23022319
UniProtQ9X4C9|DNAB_GEOSE Replicative DNA helicase DnaB (Gene Name=dnaB)

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