Structure of PDB 5w7b Chain D Binding Site BS04

Receptor Information
>5w7b Chain D (length=412) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDS
DKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIIL
LGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLD
SENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPA
IVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHV
ILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWM
SANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQ
KMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNP
QIEEVFGDQGGH
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain5w7b Chain D Residue 620 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w7b Crystal structure of the mammalian lipopolysaccharide detoxifier.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		G340 N372 R378
Binding residue
(residue number reindexed from 1)		G177 N209 R215
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.77: acyloxyacyl hydrolase.
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0050528 acyloxyacyl hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5w7b, PDBe:5w7b, PDBj:5w7b
PDBsum5w7b
PubMed29343645
UniProtO18823|AOAH_RABIT Acyloxyacyl hydrolase (Gene Name=AOAH)

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