Structure of PDB 5w4t Chain D Binding Site BS04

Receptor Information
>5w4t Chain D (length=315) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNQPPRFQNYFFQSYLLVYEDTPVGTSITQLQAVDPDGEPLIFGVVGEEA
MRYFAVQGTTGVVWLRQPLDREAKSEMQVEFTVSDSQGVVKDTVNIQIGD
VNDNAPSFYNQPYAIQIPENTPVGTSVFMVNATDPDQGVGGSVLFSFQPP
SQFFSIDGARGIVTVTRALDYETTIAYQLTVNATDQDKRRPLSSLANLAI
TITDIQDMDPIFTNLPYSTNIMEDAPPGYEVRKIRAIDQDLGRPRGIGYT
IISGNTNSMFALDYISGSLTVSGQLDRENPLYSSGFIITVKATELNDDRT
PSSATVTTTFTILLI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5w4t Chain D Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5w4t Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		E118 D169 E171 D206
Binding residue
(residue number reindexed from 1)		E119 D170 E172 D207
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5w4t, PDBe:5w4t, PDBj:5w4t
PDBsum5w4t
PubMed30033219
UniProtF1R7G8

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