Structure of PDB 5czr Chain D Binding Site BS04

Receptor Information
>5czr Chain D (length=216) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNVAPKFLANMTSVILPEDLPVGAQAFWLVAEDQDNDPLTYGMSGPNAYF
FAVTPKTGEVKLASALDYETLYTFKVTISVSDPYIQVQREMLVIVEDRND
NAPVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPS
TGDSEHLFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTI
QCSLPVFLSISVVDQP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5czr Chain D Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5czr Crystal Structure of Human Protocadherin-24 EC1-2
Resolution2.3 Å
Binding residue
(original residue number in PDB)		N98 N100 D130 D132 A136 D188
Binding residue
(residue number reindexed from 1)		N99 N101 D131 D133 A137 D189
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5czr, PDBe:5czr, PDBj:5czr
PDBsum5czr
PubMed
UniProtQ9BYE9|CDHR2_HUMAN Cadherin-related family member 2 (Gene Name=CDHR2)

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