Structure of PDB 4bw5 Chain D Binding Site BS04

Receptor Information
>4bw5 Chain D (length=250) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHV
CVSPQELETLIQHALDADNAGVSPISHWDLGSAFFFAGTVITTIGYGNIA
PSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKK
QVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTL
TTVGFGDFVAGGNYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKK
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain4bw5 Chain C Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4bw5 K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac
Resolution3.2 Å
Binding residue
(original residue number in PDB)		T172 T281
Binding residue
(residue number reindexed from 1)		T93 T202
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bw5, PDBe:4bw5, PDBj:4bw5
PDBsum4bw5
PubMed25766236
UniProtP57789|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)

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