Structure of PDB 3ze2 Chain D Binding Site BS04

Receptor Information

>3ze2 Chain D (length=367) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SEARVLEDRPLSDVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYY
LMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMY
ISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNR
DAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIV
QPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVN
LYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEEL
SLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTI
KPVGFKDSLIVQVTFDC

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

3ze2 Chain D Residue 2003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3ze2 Complete Integrin Headpiece Opening in Eight Steps.
Resolution	2.35 Å
Binding residue (original residue number in PDB)	D158 N215 D217 P219 E220
Binding residue (residue number reindexed from 1)	D92 N149 D151 P153 E154
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:3ze2, PDBe:3ze2, PDBj:3ze2
PDBsum	3ze2
PubMed	23798730
UniProt	P05106\|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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