Structure of PDB 1izl Chain D Binding Site BS04

Receptor Information
>1izl Chain D (length=277) Species: 197221 (Thermosynechococcus vestitus BP-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GILLFPCAYLALGGWLTGTTFVTSWYTHGLASSYLEGCNFLTVAVSTEAQ
GDFTRWCQLGGLWTFIALHGAFGLIGFMLRQFEIARLVGVRPYNAIAFSA
PIAVFVSVFLIYPLGFAPSFGVAAIFRFLLFFQGFHNWTLNPFHMMGVAG
VLGGALLCAIHGATVENTYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVP
VTGLWMSAIGVVGLALNLRSYDFISQEIRAAEDPEFETFYTKNLLLNEGI
RAWMAPQDQPHENFVFPEEVLPRGNAL
Ligand information
Ligand IDPLA
InChIInChI=1S/C13H19N2O9P/c1-7-11(18)9(8(4-14-7)6-24-25(21,22)23)5-15-13(2,12(19)20)3-10(16)17/h4,15,18H,3,5-6H2,1-2H3,(H,16,17)(H,19,20)(H2,21,22,23)/t13-/m0/s1
InChIKeyZFKRUCNEKPIDBK-ZDUSSCGKSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(CN[C@@](C)(CC(O)=O)C(O)=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)CNC(C)(CC(=O)O)C(=O)O)O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)CN[C@@](C)(CC(=O)O)C(=O)O)O
ACDLabs 10.04O=C(O)C(NCc1c(cnc(c1O)C)COP(=O)(O)O)(C)CC(=O)O
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(CN[C](C)(CC(O)=O)C(O)=O)c1O
FormulaC13 H19 N2 O9 P
Name2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID;
N-PYRIDOXYL-2-METHYLASPARTIC ACID-5-MONOPHOSPHATE
ChEMBL
DrugBank
ZINCZINC000003870760
PDB chain1izl Chain D Residue 358 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1izl Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution
Resolution3.7 Å
Binding residue
(original residue number in PDB)		H214 T217
Binding residue
(residue number reindexed from 1)		H161 T164
Annotation score1
Enzymatic activity
Enzyme Commision number 1.10.3.9: photosystem II.
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0010242 oxygen evolving activity
GO:0016168 chlorophyll binding
GO:0016491 oxidoreductase activity
GO:0045156 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GO:0046872 metal ion binding
Biological Process
GO:0009772 photosynthetic electron transport in photosystem II
GO:0015979 photosynthesis
GO:0019684 photosynthesis, light reaction
Cellular Component
GO:0009523 photosystem II
GO:0009579 thylakoid
GO:0016020 membrane
GO:0031676 plasma membrane-derived thylakoid membrane
GO:0042651 thylakoid membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1izl, PDBe:1izl, PDBj:1izl
PDBsum1izl
PubMed12518057
UniProtQ8CM25|PSBD_THEVB Photosystem II D2 protein (Gene Name=psbD1)

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