Structure of PDB 1flo Chain D Binding Site BS04

Receptor Information
>1flo Chain D (length=405) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQFDILCKTPPKVLVRQFVERFERPSGEKIALCAAELTYLCWMITHNGTA
IKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWE
FTIIPYYGQKHQSDITDIVSSLQLQFESSHSKKMLKALLSEGESIWEITE
KILNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNK
YLGVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLDEFLRNSEPVLKRV
NRTGSSNKQEYQLLKDNLVRSYNKALKKNAPYSIFAIKNGPKSHIGRHLM
TSFLSMKGLTELTNVVGNWSDKRASAVARTTYTHQITAIPDHYFALVSRY
YAYDPISKEMIALKDETNPIEEWQHIEQSIRYPAWNGIISQEVLDYLSSY
INRRI
Ligand information
Ligand IDPHS
InChIInChI=1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3)
InChIKeyABLZXFCXXLZCGV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0OP(=O)O
ACDLabs 10.04O=P(O)O
CACTVS 3.341O[PH](O)=O
FormulaH3 O3 P
NamePHOSPHONIC ACID
ChEMBLCHEMBL1235291
DrugBank
ZINCZINC000245204350
PDB chain1flo Chain K Residue -4 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1flo Crystal structure of a Flp recombinase-Holliday junction complex: assembly of an active oligomer by helix swapping.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		R191 H305
Binding residue
(residue number reindexed from 1)		R182 H294
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0008301 DNA binding, bending
GO:0009009 site-specific recombinase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0042150 plasmid recombination
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1flo, PDBe:1flo, PDBj:1flo
PDBsum1flo
PubMed11090626
UniProtP03870|FLP_YEAST Site-specific recombinase Flp (Gene Name=FLP1)

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