Structure of PDB 1aei Chain D Binding Site BS04

Receptor Information
>1aei Chain D (length=315) Species: 6087 (Hydra vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQI
KTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGL
GTDENALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLL
VSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSY
PQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAE
RLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADD
CSGDYKDLLLQITGH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1aei Chain D Residue 320 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1aei Crystal structure of the annexin XII hexamer and implications for bilayer insertion.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		M257 K258 G259 G261 D301
Binding residue
(residue number reindexed from 1)		M256 K257 G258 G260 D300
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1aei, PDBe:1aei, PDBj:1aei
PDBsum1aei
PubMed7477411
UniProtP26256|ANX12_HYDVU Annexin-B12 (Gene Name=ANXB12)

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