Structure of PDB 8jwj Chain C Binding Site BS04

Receptor Information
>8jwj Chain C (length=272) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPVCLLCLQEPGDPEKLGEFLQKDNLCVHYFCLILSSRLPQKGQPNRGLH
GFMPEDIKREAVRASKKICFVCKKKGAAIRCQNDQCVQNFHLPCGQERGC
LSQFFGEYKSYCRKHRPTQNIHQGSLGEESCVLCCENLSRTSVENIQSPC
CSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGIHIPDRDA
AWELEPGAFSELYQRYRHCDAPICLYEQGRDSFEDEGRWRLILCATCGSH
GTHRDCSSLRPNSKKWECNECL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8jwj Chain C Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8jwj Molecular basis for PHF7-mediated ubiquitination of histone H3.
Resolution2.96 Å
Binding residue
(original residue number in PDB)		C160 C163 H186 C189
Binding residue
(residue number reindexed from 1)		C131 C134 H157 C160
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016607 nuclear speck

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jwj, PDBe:8jwj, PDBj:8jwj
PDBsum8jwj
PubMed37993255
UniProtQ9DAG9|PHF7_MOUSE PHD finger protein 7 (Gene Name=Phf7)

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