Structure of PDB 8ibw Chain C Binding Site BS04

Receptor Information
>8ibw Chain C (length=922) Species: 7091 (Bombyx mori) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GWTCQFCERTFSTNRGLGVHKRRAHPVETNTDAAPMMVKRRWHGEEIDLL
ARTEARLLAERGQCSGGDLFGALPGFGRTLEAIKGQRRREPYRALVQAHL
ARFGSSPDAARVLSELLEGAGRRRACRAMTSRQKRRAEYARVQELYKKCR
SRAAAEVIDGACGGVGHSLEEMETYWRPILERVSDAPGPTPEALHALGRT
QLWKPISVEEIKASRFDWRTSPGPDGIRSGQWRAVPVHLKAEMFNAWMAR
GEIPEILRQCRTVFVPKVERPGGPGEYRPISIASIPLRHFHSILARRLLA
CCPPDARQRGFICADGTLENSAVLDAVLGDSRKKLRECHVAVLDFAKAFD
TVSHEALVELLRLRGMPEQFCGYIAHLYDTASTTLAVNNEMSSPVKVGRG
VRQGDPLSPILFNVVMDLILASLPERVGYRLEMELVSALAYAYDLVLLAG
SKVGMQESISAVDCVGRQMGLRLNCRKSAVLSMIPDGHRKKHHYLTERTF
NIGGKPLRQVSCVERWRYLGVDFEASGCVTLEHSISSALNNISRAPLKPQ
QRLEILRAHLIPRFQHGFVLGNISDDRLRMLDVQIRKAVGQWLRLPADVP
KAYYHAAVQDGGLAIPSVRATIPDLIVRRFGGLDSSPWSVARAAAKSDKI
RKKLRWAWKQLRRFSRVDSTTQRPSVRLFWREHLHASVDGRELRESTRTP
TSTKWIRERCAQITGRDFVQFVHTHINALPSRIRGSRGRRGGGESSLTCR
AGCKVRETTAHILQQCHRTHGGRILRHNKIVSFVAKAMEENKWTVELEPR
LRTSVGLRKPAIIASRDGVGVIVDVQVVSGQRSLDELHREKRNKYGNHGE
LVELVAGRLGLPKAECVRATSCTISWRGVWSLTSYKELRSIIGLREPTLQ
IVPILALRGSHMNWTRFNQMTS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8ibw Chain C Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ibw Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
C114 C117 H130 H135
Binding residue
(residue number reindexed from 1)
C4 C7 H20 H25
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003964 RNA-directed DNA polymerase activity
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0071897 DNA biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:8ibw, PDBe:8ibw, PDBj:8ibw
PDBsum8ibw
PubMed37301196
UniProtV9H052

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