Structure of PDB 8edg Chain C Binding Site BS04

Receptor Information
>8edg Chain C (length=550) Species: 7370 (Musca domestica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDNLEVKAKINQGLYKITPRHKGTSFIWNVLADIQKEDDTLVEGWVFCRK
CEKVLKYTTRQTSNLCRHKCCASLKQSRELKTVSADCKKEAIEKCAQWVV
RDCRPFSAVSGSGFIDMIKFFIKVGAEYGEHVNVEELLPSPITLSRKVTS
DAKEKKALISREIKSAVEKDGASATIDLWTDNYIKRNFLGVTLHYHENNE
LRDLILGLKSLDFERSTAENIYKKLKAIFSQFNVEDLSSIKFVTDRGANV
VKSLANNIRINCSSHLLSNVLENSFEETPELNMPILACKNIVKYFKKANL
QHRLRSSLKSECPTRWNSTYTMLRSILDNWESVIQILSEAGETQRIVHIN
KSIIQTMVNILDGFERIFKELQTCSSPSLCFVVPSILKVKEICSPDVGDV
ADIAKLKVNIIKNVRIIWEENLSIWHYTAFFFYPPALHMQQEKVAQIKEF
CLSKMEDPVCPSDEFEFYRKEIVILSEDFKVMEWWNLNSKKYPKLSKLAL
SLLSIPASSAASERTFSLAGNIITEKRNRIGQQTVDSLLFLNSFYKNFCK
Ligand information
>8edg Chain R (length=55) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caagtggcgcataagtatcaaaataagccacttgttgttgttctctggtt
cacgc
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8edg Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Resolution4.64 Å
Binding residue
(original residue number in PDB)		G26 T27 S28 R63 Q64 S66 P108 F109 S110 W319 R573
Binding residue
(residue number reindexed from 1)		G23 T24 S25 R60 Q61 S63 P105 F106 S107 W316 R514
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8edg, PDBe:8edg, PDBj:8edg
PDBsum8edg
PubMed37491363
UniProtQ25438

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