Structure of PDB 7uyz Chain C Binding Site BS04
Receptor Information
>7uyz Chain C (length=337) Species:
10090
(Mus musculus) [
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KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQSEFKGVEQLNTGSYY
EHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVPLSHFVLSATKMLS
KFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEISVDIILALES
KGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAFQGETWRLSFSH
TEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFC
SYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYF
IPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFDK
Ligand information
>7uyz Chain J (length=18) [
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atctgtacatgtacagat
Receptor-Ligand Complex Structure
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PDB
7uyz
Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG
Resolution
2.49 Å
Binding residue
(original residue number in PDB)
R161 S165 A168 N196 Y200 K372
Binding residue
(residue number reindexed from 1)
R13 S17 A20 N45 Y49 K203
Enzymatic activity
Enzyme Commision number
2.7.7.86
: cyclic GMP-AMP synthase.
External links
PDB
RCSB:7uyz
,
PDBe:7uyz
,
PDBj:7uyz
PDBsum
7uyz
PubMed
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
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