Structure of PDB 7lo5 Chain C Binding Site BS04

Receptor Information
>7lo5 Chain C (length=1014) Species: 980427 (Deinococcus wulumuqiensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLQLVKKFQKRLEDIVAYGGTRNESSVRAAFQQLLSDWAEGSGLRLITE
VTQKAVAGNNVRPDGTLKDSLQQSRGYWESKDEADTLDDEIQKKLAKGYP
RDNIIFEDSRLAVLMQNGEEVQRVDMGDAGALAGLLKLFFEFEPPQVLEF
RKAVDHFKDEMPHLLKILREAADAAEQKADYRGERDHFVEIAKEAINPDF
SPRDAREMLIQHILTGDLFTSVFDNAQYHEDNNIAQQLQQLAATFYKGPV
KRDIAERTKRYYGAIQAAAAQIADHHEKQRFLKALYENFYRAYNPAGAER
LGIFYTPGEIVRFMIEATDTLLEKHFQKELADKGVEILDPATGTGTFITE
LIDFLPKAKLEQKYREELHCNELALLPYYIANLNIEATYAQKMGRYEEFR
NIVLVDTLDNTSGLFGSVTAENLERAKRQNARPVRVIIGNPPYRANQANE
NDNNKNREYKEIDRRIKATYVAASTAQKTKLYDMYSRFLRWATDRLKEDG
IVAFVSNSSFIDSRTFDGFRKEVVKDFDHIYILDMKGNANTSGERRKREG
GNVFNDQIKVGVAVYFLVRSADTKIWYHAVPDFWRAREKLEWLKTTKFED
IEFDHIRPDAKHNWLGQVDEENDWNEFLPVADKDTKQAKGLGQERAIFKL
YSLGVVTNRDEWVYSRAEDELADKVRYFIGRYNEIIKLPLGDLMSRNWEG
DIKMTRATIADAQSRKSYSLEKNSIVPSLYRPFDVLKMYFSKNLNEMQYQ
MPSIFPKGVGENVVIALSGSPAAKPFQVLATDILPSLDLLEKTQCLPFYR
YTMNGERLNNITDYALKAFQTHYADTSISREDIFHYVYAVLHHPAYREKY
ALNLRQEFPRIPFYPEFGRWAAWGRELMALHIGFESVAPYPLKRTDEPPK
NDTPEALALAKKARLKVQRDAAKQPTGAVELDGLTTLAGIPAAAWAYKLG
NRSALEWVLERHKETTPKDATIREKFNTYRFADHKERVIDLLARVTTVSV
ETVRIVGEMPAETM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7lo5 Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		N454 Q455 N457 E458 K463 K475 Q485 K486 T487 Y490 A547 N548 T549 R554 K651 N673 D675 K718 R721 R746 D803
Binding residue
(residue number reindexed from 1)		N446 Q447 N449 E450 K455 K467 Q477 K478 T479 Y482 A539 N540 T541 R546 K636 N658 D660 K703 R706 R731 D788
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7lo5, PDBe:7lo5, PDBj:7lo5
PDBsum7lo5
PubMed33826880
UniProtA0A345IJ72

[Back to BioLiP]