Structure of PDB 6vfu Chain C Binding Site BS04

Receptor Information
>6vfu Chain C (length=428) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHL
VDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKD
LNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPN
ELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGT
VGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNG
QVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDL
GPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALV
RVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNL
TIQARDGGVPMLQSAKSFTVLITDHHHH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6vfu Chain C Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6vfu Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		E119 D176 E178 D212
Binding residue
(residue number reindexed from 1)		E119 D176 E178 D212
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vfu, PDBe:6vfu, PDBj:6vfu
PDBsum6vfu
PubMed32101743
UniProtQ8TAB3|PCD19_HUMAN Protocadherin-19 (Gene Name=PCDH19)

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