Structure of PDB 6sei Chain C Binding Site BS04

Receptor Information

>6sei Chain C (length=270) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QCKPIPALYTVYVLRSTVRHASLYIGSTPNPPRRLKQHNGLVPGGAARTS
RSSLRPWEMVALVSGFPSMVAALKFQWALTNPHLSVHIPSASRPQRPPRS
LASVVANLHLLLRVPSFARWPLRVHFFRRDVFAAWEKWCAAASERLRPSL
AVVTDFEGGCWGIHALPLDYEPIKDYVAKGQEIFEFERQGACVVCREEMA
SGDGLQALCTNQGCDGVGHLSCWSRHFLKDSILPVQGQCPKCGGEMEWGN
MMKELTLRTRGQKEVEKLLK

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6sei Chain C Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6sei Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.
Resolution	2.69 Å
Binding residue (original residue number in PDB)	F171 G173
Binding residue (residue number reindexed from 1)	F156 G158
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.1.-.-

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity
GO:0004520	DNA endonuclease activity
GO:0008821	crossover junction DNA endonuclease activity
GO:0017108	5'-flap endonuclease activity
GO:0046872	metal ion binding

	Biological Process
GO:0000724	double-strand break repair via homologous recombination
GO:0006281	DNA repair
GO:0006310	DNA recombination

	Cellular Component
GO:0005634	nucleus
GO:0033557	Slx1-Slx4 complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:6sei, PDBe:6sei, PDBj:6sei
PDBsum	6sei
PubMed	31584081
UniProt	G2QV68

[Back to BioLiP]