Structure of PDB 6cim Chain C Binding Site BS04

Receptor Information
>6cim Chain C (length=602) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEH
RQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQ
IFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSV
DEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVV
KESCDGMGDVSEKVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELC
CKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFI
FRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHA
ENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNA
AEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNG
NFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKE
CPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDG
SIGAWNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNA
HN
Ligand information
>6cim Chain J (length=52) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ctggcctgtcttacacagtgatgcaaatcaagtgtgaagccagacaaaaa
cc
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6cim Cracking the DNA Code for V(D)J Recombination.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		R440 A441 N443 I846 M847 R848 N850 K966
Binding residue
(residue number reindexed from 1)		R45 A46 N48 I445 M446 R447 N449 K561
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6cim, PDBe:6cim, PDBj:6cim
PDBsum6cim
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

[Back to BioLiP]