Structure of PDB 4bw5 Chain C Binding Site BS04
Receptor Information
>4bw5 Chain C (length=233) Species:
9606
(Homo sapiens) [
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KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHV
CVSPQELETLIQHALDADNAGVSPIGNSSHWDLGSAFFFAGTVITTIGYG
NIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIAIRVIST
ILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGG
NEWYKPLVWFWILVGLAYFAAVLSMIGDWLRVL
Ligand information
Ligand ID
K
InChI
InChI=1S/K/q+1
InChIKey
NPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[K+]
Formula
K
Name
POTASSIUM ION
ChEMBL
CHEMBL1233793
DrugBank
DB01345
ZINC
PDB chain
4bw5 Chain C Residue 603 [
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Receptor-Ligand Complex Structure
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PDB
4bw5
K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
T172 T281
Binding residue
(residue number reindexed from 1)
T96 T190
Annotation score
5
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005267
potassium channel activity
Biological Process
GO:0071805
potassium ion transmembrane transport
Cellular Component
GO:0016020
membrane
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Cellular Component
External links
PDB
RCSB:4bw5
,
PDBe:4bw5
,
PDBj:4bw5
PDBsum
4bw5
PubMed
25766236
UniProt
P57789
|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)
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