Structure of PDB 2uzp Chain C Binding Site BS04

Receptor Information
>2uzp Chain C (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLI
PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTS
RNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2uzp Chain C Residue 1297 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2uzp Crystal Structure of C2 Domain of Protein Kinase C Gamma
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D248 S251 R252 D254
Binding residue
(residue number reindexed from 1)		D97 S100 R101 D103
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.13: protein kinase C.
External links
PDB RCSB:2uzp, PDBe:2uzp, PDBj:2uzp
PDBsum2uzp
PubMed
UniProtP05129|KPCG_HUMAN Protein kinase C gamma type (Gene Name=PRKCG)

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