Structure of PDB 2rib Chain C Binding Site BS04

Receptor Information
>2rib Chain C (length=150) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFT
EAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFT
YPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF
Ligand information
Ligand IDGMH
InChIInChI=1S/C7H14O7/c8-1-2(9)6-4(11)3(10)5(12)7(13)14-6/h2-13H,1H2/t2-,3-,4-,5-,6+,7-/m0/s1
InChIKeyBGWQRWREUZVRGI-QQABCQGCSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC[C@H](O)[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C(C(C1C(C(C(C(O1)O)O)O)O)O)O
CACTVS 3.341OC[CH](O)[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)C(O)CO
OpenEye OEToolkits 1.5.0C([C@@H]([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O)O
FormulaC7 H14 O7
NameL-glycero-alpha-D-manno-heptopyranose;
L-glycero-alpha-D-manno-heptose;
L-glycero-D-manno-heptose;
L-glycero-manno-heptose;
L-GLYCERO-D-MANNO-HEPTOPYRANOSE
ChEMBL
DrugBankDB04526
ZINC
PDB chain2rib Chain C Residue 356 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2rib Recognition of heptoses and the inner core of bacterial lipopolysaccharides by surfactant protein d.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		E321 N323 D325 E329 N341
Binding residue
(residue number reindexed from 1)		E116 N118 D120 E124 N136
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2rib, PDBe:2rib, PDBj:2rib
PDBsum2rib
PubMed18092821
UniProtP35247|SFTPD_HUMAN Pulmonary surfactant-associated protein D (Gene Name=SFTPD)

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