Structure of PDB 2ox8 Chain C Binding Site BS04

Receptor Information
>2ox8 Chain C (length=129) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIK
KQMVGRESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPG
EDCAGLIYAGQWNDFQCEDVNNFICEKDR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2ox8 Chain C Residue 8 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ox8 Scavenger receptor C-type lectin binds to the leukocyte cell surface glycan Lewis(x) by a novel mechanism.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		E674 D707
Binding residue
(residue number reindexed from 1)		E69 D102
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2ox8, PDBe:2ox8, PDBj:2ox8
PDBsum2ox8
PubMed17420244
UniProtQ5KU26|COL12_HUMAN Collectin-12 (Gene Name=COLEC12)

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