Structure of PDB 2obe Chain C Binding Site BS04

Receptor Information
>2obe Chain C (length=909) Species: 175567 (Simian adenovirus 25) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLPQWAYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPTHD
VTTDRSQRLTLRFVPVDREDNTYSYKVRYTLAVGDNRVLDMASTYFDIRG
VLDRGPSFKPYSGTAYNSLAPKGAPNTCQWTYKTEKTYTYGNAPVQGINI
TKDGIQLGTDTDDQPIYADKTYQPEPQVGDAEWHEKYGGRALKPDTKMKP
CYGSFAKPTNKEGGQANVKTGTGTTKEYDIDMAFFDNRSAAAAGLAPEIV
LYTENVDLETPDTHIVYKAGTDDSSSSINLGQQAMPNRPNYIGFRDNFIG
LMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSLGDRTRYFS
MWNQAVDSYDPDVRIIENHGVEDELPNYCFPLDAVGRTDTYQGIKANTTW
TKDDSVNDANEIGKGNPFAMEINIQANLWRNFLYANVALYLPDSYKYTPA
NVTLPTNTNTYDYMNGRVVAPSLVDSYINIGARWSLDPMDNVNPFNHHRN
AGLRYRSMLLGNGRYVPFHIQVPQKFFAIKSLLLLPGSYTYEWNFRKDVN
MILQSSLGNDLRTDGASISFTSINLYATFFPMAHNTASTLEAMLRNDTND
QSFNDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWSFTRLKTKETPS
LGSGFDPYFVYSGSIPYLDGTFYLNHTFKKVSITFDSSVSWPGNDRLLTP
NEFEIKRTVDGEGYNVAQCNMTKDWFLVQMLAHYNIGYQGFYVPEGYKDR
MYSFFRNFQPMSRQVVDEVNYKDYQAVTLAYQHNNSGFVGYLAPTMRQGQ
PYPANYPYPLIGKSAVTSVTQKKFLCDRVMWRIPFSSNFMSMGALTDLGQ
NMLYANSAHALDMNFEVDPMDESTLLYVVFEVFDVVRVHQPHRGVIEAVY
LRTPFSAGN
Ligand information
Ligand ID2HP
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0OP(=O)(O)[O-]
ACDLabs 10.04[O-]P(=O)(O)O
CACTVS 3.341O[P](O)([O-])=O
FormulaH2 O4 P
NameDIHYDROGENPHOSPHATE ION
ChEMBL
DrugBankDB02831
ZINC
PDB chain2obe Chain C Residue 1618 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2obe Structure-based identification of a major neutralizing site in an adenovirus hexon
Resolution2.1 Å
Binding residue
(original residue number in PDB)		T57 D58 R59 A603 H604
Binding residue
(residue number reindexed from 1)		T53 D54 R55 A583 H584
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2obe, PDBe:2obe, PDBj:2obe
PDBsum2obe
PubMed17108028
UniProtQ8UY79

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