Structure of PDB 1lrh Chain C Binding Site BS04

Receptor Information
>1lrh Chain C (length=160) Species: 4577 (Zea mays) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCVRDNSLVRDISQMPQSSYGIEGLSHITVAGALNHGMKEVEVWLQTISP
GQRTPIHRHSCEEVFTVLKGKGTLLMGSSSLKYPGQPQEIPFFQNTTFSI
PVNDPHQVWNSDEHEDLQVLVIISRPPAKIFLYDDWSMPHTAAVLKFPFV
WDEDCFEAAK
Ligand information
Ligand IDNLA
InChIInChI=1S/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)
InChIKeyPRPINYUDVPFIRX-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1ccc2c(c1)cccc2CC(=O)O
CACTVS 3.341OC(=O)Cc1cccc2ccccc12
ACDLabs 10.04O=C(O)Cc2cccc1ccccc12
FormulaC12 H10 O2
NameNAPHTHALEN-1-YL-ACETIC ACID
ChEMBLCHEMBL428495
DrugBankDB01750
ZINCZINC000000391809
PDB chain1lrh Chain C Residue 7190 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lrh Crystal structure of auxin-binding protein 1 in complex with auxin.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		W44 Q46 T54 P55 H57 E63 F149
Binding residue
(residue number reindexed from 1)		W44 Q46 T54 P55 H57 E63 F149
Annotation score1
Binding affinityMOAD: Kd=0.15uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0010011 auxin binding
GO:0046872 metal ion binding
Biological Process
GO:0000911 cytokinesis by cell plate formation
GO:0009734 auxin-activated signaling pathway
GO:0009826 unidimensional cell growth
GO:0032877 positive regulation of DNA endoreduplication
GO:0045793 positive regulation of cell size
GO:0051781 positive regulation of cell division
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen

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Biological Process
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Cellular Component
External links
PDB RCSB:1lrh, PDBe:1lrh, PDBj:1lrh
PDBsum1lrh
PubMed12065401
UniProtP13689|ABP1_MAIZE Auxin-binding protein 1 (Gene Name=ABP1)

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