Structure of PDB 7o80 Chain Bz Binding Site BS04

Receptor Information
>7o80 Chain Bz (length=595) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISET
LCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPG
EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQ
NYFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQ
LDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRL
KAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPF
SVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGM
KKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGE
VPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIEN
IIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARV
VKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLA
GMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLD
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7o80 Chain Bz Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7o80 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C16 C21 C25 C65 L70
Binding residue
(residue number reindexed from 1)		C13 C18 C22 C62 L67
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0006413 translational initiation
GO:0006415 translational termination

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7o80, PDBe:7o80, PDBj:7o80
PDBsum7o80
PubMed34029205
UniProtG1SG72

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