Structure of PDB 9ftw Chain B Binding Site BS04

Receptor Information
>9ftw Chain B (length=279) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETRNQVDR
CPKPLFTYVNEKLFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAF
LREIMKTAVMKELYSFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDS
SGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPD
VLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGY
PLAVRTYTWDKSTYGNGKKYIATAYIVSS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain9ftw Chain B Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB9ftw Molecular Basis for the Calcium-Dependent Activation of the Ribonuclease EndoU.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		Q210 E217 D279 E284
Binding residue
(residue number reindexed from 1)		Q80 E87 D149 E154
Annotation score1
External links
PDB RCSB:9ftw, PDBe:9ftw, PDBj:9ftw
PDBsum9ftw
PubMed39070628
UniProtP21128|ENDOU_HUMAN Uridylate-specific endoribonuclease (Gene Name=ENDOU)

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