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Receptor Information

>8wd8 Chain B (length=750) Species: 277988 (Thermococcus thioreducens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MLMKVLTNMVKLNQDIIPNEIYLYKIFNKPEDGMNIYKIAYRNHGIVIDP
QNRIIATPSELEYSGKFAIEDEISFNELPENYQNRLVLRILRDNGISDHA
LSRTLQKYRKPKPFGDFEVIPEIRSSVIKHGGDFYLVLHLSHQIRSKKTL
WELVGRNKDALRDFLKEHRGTILLRDIASEHKVVYKPIFKRYNGDPDLIE
DNSNDVEHWYDYHLERYWNTPELKKEFYKKFGPVDLNQPIILAKPLRQHN
RGDLVHLLPQFVVPVYNAEQLNDILASEILEYLKLTSNQRISLLSRLIND
IKTNTNIIVSSLTELEANTFDVDLNDMLQVRNADNVKVTLSELEISKTRL
FTWMKSRKYPVILPYDIPQKLKKIEKIPVFIIVDSALSRDIQTFAKDEFR
YLISSLQKSLSNWVDFPILDIRDKYIFTIDLTSDKDIVNLSIKLVNLMKN
AELGLALIATRTKLPNETFDEVKKRLFSVNIISQVVNEATLYKRDKYNES
RLNLYVQHNLLFQILSKLGIKYYVLRHKFSYDYIVGIDVTPMKLSHGYIG
GSAVMFDSQGYIRKIIPVEIGEQMGESIDMKEFFKDMVVQFGKFGIDLEG
KSILILRDGKITKDEEEGLAYISKVFGIKITTFNIVKRHLLRIFANRKLY
LRLANSVYLLPHRIKQSVGTPVPLKLSEKRLILDGTITSQEITYNDIFEI
LLLSELNYGSISADMKLPAPVHYAHKFVRALRKGWRIREELLAEGFLYFV

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8wd8 Chain B Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8wd8 Molecular mechanism for target recognition, dimerization, and activation of Pyrococcus furiosus Argonaute.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	Q513 V750
Binding residue (residue number reindexed from 1)	Q513 V750
Annotation score	4

Enzyme Commision number

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding

PDB	RCSB:8wd8, PDBe:8wd8, PDBj:8wd8
PDBsum	8wd8
PubMed	38295801
UniProt	A0A0Q2M2Z1

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Structure of PDB 8wd8 Chain B Binding Site BS04