Structure of PDB 8tcm Chain B Binding Site BS04

Receptor Information
>8tcm Chain B (length=313) Species: 672471 (HIV whole-genome vector AA1305#18) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKIS
KIGPENPYNTPVFAIKTKWRKLVDFRELNKRTQDFPHPAGLKKKKSVTVL
DVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI
FQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKISELRQHL
LRWGLTTPDGYELHPDKWTGYDPSDLIAEIQKQGQGQWTYQIYQNLKTGK
YARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWT
EYWQATWIPEWEF
Ligand information
Ligand IDZQT
InChIInChI=1S/C13H10O5/c14-6-1-10(16)8-5-9-11(17)2-7(15)4-13(9)18-12(8)3-6/h1-4,14-17H,5H2
InChIKeyWRWDLBILCDUPOS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385Oc1cc(O)c2Cc3c(O)cc(O)cc3Oc2c1
OpenEye OEToolkits 2.0.7c1c(cc2c(c1O)Cc3c(cc(cc3O2)O)O)O
ACDLabs 12.01Oc1cc(O)cc2Oc3cc(O)cc(O)c3Cc21
FormulaC13 H10 O5
Name9H-xanthene-1,3,6,8-tetrol
ChEMBL
DrugBank
ZINC
PDB chain8tcm Chain B Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8tcm Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and xanthene bound
Resolution1.82 Å
Binding residue
(original residue number in PDB)		G152 K154 P157 M184 D185 W410
Binding residue
(residue number reindexed from 1)		G143 K145 P148 M175 D176 W307
Annotation score1
External links
PDB RCSB:8tcm, PDBe:8tcm, PDBj:8tcm
PDBsum8tcm
PubMed
UniProtP04585|POL_HV1H2 Gag-Pol polyprotein (Gene Name=gag-pol)

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