Structure of PDB 8qz2 Chain B Binding Site BS04

Receptor Information
>8qz2 Chain B (length=246) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCV
SPQELETLIQHALDADNAGVSPIGQSSQQSSHWDLGSAFFFAGTVITTIG
YGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEK
VFVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVT
LTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIG
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain8qz2 Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qz2 Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		T172 I173 T281
Binding residue
(residue number reindexed from 1)		T98 I99 T203
Annotation score3
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8qz2, PDBe:8qz2, PDBj:8qz2
PDBsum8qz2
PubMed38755204
UniProtP57789|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)

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