Structure of PDB 8q9r Chain B Binding Site BS04

Receptor Information
>8q9r Chain B (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKK
Ligand information
Receptor-Ligand Complex Structure
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PDB8q9r Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		V19 T22 K23
Binding residue
(residue number reindexed from 1)		V18 T21 K22
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8q9r, PDBe:8q9r, PDBj:8q9r
PDBsum8q9r
PubMed38492719
UniProtQ05BX2

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