Structure of PDB 8pt6 Chain B Binding Site BS04

Receptor Information

>8pt6 Chain B (length=515) Species: 1549864 (Tilapia lake virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MWAFQEGVCKGNLLSGPTSMKAPDSAARESIDRASEIMTGKSYNAVHTGD
LSKLPNQGESPLRIVDSDLYSERSCCWVIEKEGRVVCKSTTLTRGMTSLL
NTTKCSSPSELICKVLTVESLSEKIGDTSVEELLSHGRYFKCALRDQERG
KPKSRAIFLSHPFFRLLSSVVETHARSVLSKVSAVYTATASAEQRAMMAA
QVVESRKHVLNGDCTKYNEAIDADTLLKVWDAIGMGSIGVMLAYMVRRKC
VLIKDTLVECPGGMLMGMFNATATLALQGTTDRFLSFSDDFITSFNSPAE
LREIEDLLFASCHNLSLKKSYISVASLEINSCTLTRDGDLATGLGCTAGV
PFRGPLVTLKQTAAMLSGAVDSGVMPFHSAERLFQIKQQECAYRYNNPTY
TTRNEDFLPTCLGGKTVISFQSLLTWDCHPFWYQVHPDGPDTIDQKVLSV
LASKTRRRRTRLEALSDLDPLVPHRLLVSESDVSKIRAARQAHLKSLGLE
QPTNFNYAIYKAVQP

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8pt6 Chain F Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8pt6 Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Resolution	3.03 Å
Binding residue (original residue number in PDB)	D213 C214 D289
Binding residue (residue number reindexed from 1)	D213 C214 D289
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003968	RNA-dependent RNA polymerase activity

	Biological Process
GO:0001172	RNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:8pt6, PDBe:8pt6, PDBj:8pt6
PDBsum	8pt6
PubMed	38066000
UniProt	A0A1Y9SHW4

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