Structure of PDB 8p4g Chain B Binding Site BS04

Receptor Information
>8p4g Chain B (length=434) Species: 178306 (Pyrobaculum aerophilum str. IM2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSAPVPPLIKEATYIEATASGYMAEGVLNPTIILRRGQRVDMTLKNKLTE
PTIVHWHGFDVNWHNDAHPSFAITPGESYNYSFDVVNRAGTYLYHPHPHG
LTAKQFYMGQLGLVIVEDSGSDLGFKYGVNDLPLVISDRRFIGGAPVYNP
TPMEMIAGFLGNAVLVNGIKDAVFKLSGGSYRLRLVNGSNARLYMLSIVK
KNGDVVPMRLIAVDQGFLARPIEVRALFLAPAERAEVVVELGEGVYLLKN
TPFDHMHLQEALPEGSEYTIATFLVEGKGEAVPVEALPDPPPEPPKPTRT
RRFALSLSGMQWTINGMSWNASNPLFEHVSVEGVELWEIVNDKASMTHPV
HLHGFPMWIIERKDSPRQVAELAVDNRGRLPTDLGLKDTVLIWPGETVKI
VVNFDAKKRGQLFPFHCHNLEHEDGGMMINIAVK
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8p4g Chain B Residue 804 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8p4g Flexible active-site loops fine-tune substrate specificity of hyperthermophilic metallo-oxidases.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		H94 H132 H461
Binding residue
(residue number reindexed from 1)		H57 H95 H418
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8p4g, PDBe:8p4g, PDBj:8p4g
PDBsum8p4g
PubMed38227199
UniProtQ8ZWA8

[Back to BioLiP]