Structure of PDB 8e2l Chain B Binding Site BS04

Receptor Information

>8e2l Chain B (length=461) Species: 8187 (Lates calcarifer) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PEDEAQLIKTMFQITKVSNATLKKFGVRLFKPTKSLVFPWFAGPDSSLKG
LKLLSAQNTDTEKVTYNEATVPKISSYYNLFGLTLVGRMDSEVVLTGHEL
DTLAVSQATGLPSVALPRGVSCLPPMLLPYLEQFKRVTLWLGHDIRSWEA
SKIFSRKLGLRRCSLVRPGEDRPCPLEALARGKNLSRIIKTSIPAAHKSI
VSFKQLREDVYGELLNTEQVAGVKWTRFPELNRILKGHRKGELTVFTGPT
GSGKTTFISEVALDLCIQGVNTLWGSFQINNVRLAKIMLTQFAMQRLEEN
LEQYDFWADKFEELPLYFMTFHGQQNIKTVLDTMQHAVYLYDINHVIIDN
LQFMMGQIDKYAVQDHIIGAFRKFATNTSCHVTLIIHPRKEEDDRELQTA
SIFGSAKASQEADNVLILQEKKLVTCPGRRSLQVTKNRFDGDVGIFPLDF
IKSSLTFSAPI

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8e2l Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8e2l Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase.
Resolution	3.51 Å
Binding residue (original residue number in PDB)	T302 Q325
Binding residue (residue number reindexed from 1)	T255 Q278
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003678	DNA helicase activity
GO:0003697	single-stranded DNA binding
GO:0005524	ATP binding
GO:0043139	5'-3' DNA helicase activity

	Biological Process
GO:0006260	DNA replication

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Molecular Function

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Biological Process

External links

PDB	RCSB:8e2l, PDBe:8e2l, PDBj:8e2l
PDBsum	8e2l
PubMed	36400570
UniProt	A0A4W6C5C5

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