Structure of PDB 7r2s Chain B Binding Site BS04

Receptor Information

>7r2s Chain B (length=400) Species: 83333 (Escherichia coli K-12)

SIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTV
KHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIY
CTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDS
MMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTP
FSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQE
DRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTN
VFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGG
AVDRLSTRLQDAGFEMSLSLKAKWRPDQDALKLCREHGREIARQWALAPL

Ligand information

• Ligand ID: O
• InChI: InChI=1S/H2O/h1H2
• InChIKey: XLYOFNOQVPJJNP-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: O
  CACTVS 3.341: [O]
• Formula: O
• Name: OXYGEN ATOM
• ChEMBL: CHEMBL1098659
• DrugBank: DB09145
• PDB chain: 7r2s Chain B Residue 504

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7r2s Crystal structure of a flavodiiron protein D52K mutant from Escherichia coli pressurized with krypton gas
• Resolution: 2.194 Å
• Binding residue (original residue number in PDB): H79 E81 D83 H84 D166
• Binding residue (residue number reindexed from 1): H78 E80 D82 H83 D165
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0009055 electron transfer activity
• GO:0010181 FMN binding
• GO:0016491 oxidoreductase activity
• GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors
• GO:0016966 nitric oxide reductase activity
• GO:0042802 identical protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0046210 nitric oxide catabolic process
• GO:0071731 response to nitric oxide

Cellular Component

• GO:0005737 cytoplasm
• GO:0032991 protein-containing complex

External links

• PDB: RCSB:7r2s, PDBe:7r2s, PDBj:7r2s
• PDBsum: 7r2s
• UniProt: Q46877|NORV_ECOLI Anaerobic nitric oxide reductase flavorubredoxin (Gene Name=norV)