Structure of PDB 7d2u Chain B Binding Site BS04

Receptor Information

>7d2u Chain B (length=130) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLA
YCETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLK
NKFVEFDMKPVCKKCYEKFPLELKKRLKKL

Ligand information

InChI=1S/Zn/q+2

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Zn

Name

ZINC ION

PDB chain

7d2u Chain B Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	7d2u Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Resolution	3.15 Å
Binding residue (original residue number in PDB)	C278 C281 C300 C303
Binding residue (residue number reindexed from 1)	C90 C93 C112 C115
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:7d2u, PDBe:7d2u, PDBj:7d2u
PDBsum	7d2u
PubMed	33587032
UniProt	P48059\|LIMS1_HUMAN LIM and senescent cell antigen-like-containing domain protein 1 (Gene Name=LIMS1)

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