Structure of PDB 6tcv Chain B Binding Site BS04

Receptor Information
>6tcv Chain B (length=397) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YLRDGKSNLVSKVVELHGETYATTVKMAKVKIDAAYLETYNKAHNTDFAL
YPQDLVTFAILTAEVEMTIRAGEGLQEDKTYAIPVAIDEDAKHCIYLVKD
MRNAGDAYKGEGVMQGYLFFEVNDVNPLNTLSFQLENGKLLWDVVVLFAA
NINYDAEAGRPRVQCNPNVQYLLDNNETLLQPLRRRGVKVLLGLLGNHDI
TGLAQLSEQGAKDFAREVAQYCKAYNLDGVNYADLYSNSPDLSNPSLTNP
STAAAARLCYETKQAMPDKLVTVFDWGQMYGVATVDGVDAKEWIDIVVAN
YGSAAYPIGQMTKKQCSGISMEFNLGGGGSLSASKAQSMIDGGYGWFMGF
APSPAKYGSVFSRLQGGGEVLYGSNVAAPTIFYKKNDPTPYKYPDDL
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain6tcv Chain A Residue 8 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6tcv Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides.
Resolution1.311 Å
Binding residue
(original residue number in PDB)		E200 N202 A228 N230 N245
Binding residue
(residue number reindexed from 1)		E121 N123 A149 N151 N166
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6tcv, PDBe:6tcv, PDBj:6tcv
PDBsum6tcv
PubMed32060313
UniProtQ8A0N4

[Back to BioLiP]