Structure of PDB 6oie Chain B Binding Site BS04

Receptor Information
>6oie Chain B (length=111) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNV
KALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPK
GMWICQVCRPK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6oie Chain B Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6oie Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Resolution2.075 Å
Binding residue
(original residue number in PDB)		C216 C219 H245 C248
Binding residue
(residue number reindexed from 1)		C7 C10 H36 C39
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
External links
PDB RCSB:6oie, PDBe:6oie, PDBj:6oie
PDBsum6oie
PubMed31624313
UniProtQ8WYB5|KAT6B_HUMAN Histone acetyltransferase KAT6B (Gene Name=KAT6B)

[Back to BioLiP]