Structure of PDB 6k9z Chain B Binding Site BS04

Receptor Information
>6k9z Chain B (length=301) Species: 178306 (Pyrobaculum aerophilum str. IM2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIRKDPFTGEYILVSPCPFCPGAPETGRGWDVLILPNRYPVVTENPPEP
TAEDLYEVIPARGSSLVVVETPQHDVDDLSDLPLGQIKKILTAVAEAQRK
AEKEGNAAYFLFFRNKGKEIGVSLTHPFSQIYILPVVPPRVRAELQASYE
WYVKHGSCLHCRIVEKEEKRLVFQNRNWKAFVPFYAKWPHEVHIYPKRHR
SLLTELTDEEVADLAEALKITLCALKQVAGIPMPYIMVLHQAPLPRPTQY
YHLHFEIYGMYRPDGKLKHAAGAELGASLFTLDTTPEETAARIKAALQKC
L
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain6k9z Chain B Residue 1004 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6k9z Unique active site formation in a novel galactose 1-phosphate uridylyltransferase from the hyperthermophilic archaeon Pyrobaculum aerophilum.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		E156 H252 H266 E268
Binding residue
(residue number reindexed from 1)		E144 H240 H254 E256
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) C30 C33 H86 N127 S135 H138 F140 Q142
Catalytic site (residue number reindexed from 1) C18 C21 H74 N115 S123 H126 F128 Q130
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006012 galactose metabolic process
GO:0033499 galactose catabolic process via UDP-galactose
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6k9z, PDBe:6k9z, PDBj:6k9z
PDBsum6k9z
PubMed31693208
UniProtQ8ZXN7

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