Structure of PDB 6fws Chain B Binding Site BS04

Receptor Information
>6fws Chain B (length=683) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEEGRHLA
IEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLK
KIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQE
EQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTCPFFVARREIQE
AEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAE
ITAPWYRLQLDLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIA
SLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELF
LNDLSEKDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWA
TREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSR
LQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIAE
MAAFFREQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRY
RLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDS
PVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIY
DKRLLTKNYGKRLLDALPVFPIEQPEVPEGIVK
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain6fws Chain B Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6fws DNA translocation mechanism of an XPD family helicase.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		T56 K60 R659
Binding residue
(residue number reindexed from 1)		T55 K59 R639
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0033677 DNA/RNA helicase activity
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006281 DNA repair
GO:0009432 SOS response
GO:0032508 DNA duplex unwinding
GO:0044806 G-quadruplex DNA unwinding

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6fws, PDBe:6fws, PDBj:6fws
PDBsum6fws
PubMed30520735
UniProtP27296|DING_ECOLI ATP-dependent DNA helicase DinG (Gene Name=dinG)

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