Structure of PDB 5zln Chain B Binding Site BS04

Receptor Information

>5zln Chain B (length=753) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TLPAFLPCELKPHGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHH
LHNSDFVHLSNLRQLNLKWNCPPTGLSPLHFSCHMTIEPRTFLAMRTLEE
LNLSYNGITTVPRLPSSLVNLSLSHTNILVLDANSLAGLYSLRVLFMDGN
CYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNLTKVPRQLPPSLEYLLV
SYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPNPCIECGQKSLHLHP
ETFHHLSHLEGLVLKDSSLHTLNSSWFQGLVNMSVLDLSENFLYESIQHT
NAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFR
SLNKYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRI
SGPSTLSKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQCLSLSHN
SIAQAVQGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNS
QPFSMKGIGHNFSFVAHLSMLHSLSLAHNDIHTRVSSHLNSNSVRFLDFS
GNGMGRMWDEGGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLK
LLSLRDNYLSFFQWTSLSFLPNLEVLDLAGNQLKALTNGTLPNGTLLQKL
DVSSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLD
VRSNPLHCACGAAFVDLLLEVQTKVPGLANGVKCGSPGQLQGRSIFAQDL
RLC

Ligand information

>5zln Chain F (length=4) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tcgc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5zln Structural basis for species-specific activation of mouse Toll-like receptor 9
Resolution	2.3 Å
Binding residue (original residue number in PDB)	D259 H260 Y345 K348 V349 S350 F351 A352 F375 R377 F402
Binding residue (residue number reindexed from 1)	D232 H233 Y318 K321 V322 S323 F324 A325 F348 R350 F375

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:5zln, PDBe:5zln, PDBj:5zln
PDBsum	5zln
PubMed	29961984
UniProt	Q9EQU3\|TLR9_MOUSE Toll-like receptor 9 (Gene Name=Tlr9)

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