Structure of PDB 5xfr Chain B Binding Site BS04

Receptor Information
>5xfr Chain B (length=298) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQ
TCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDCKWLCRQCVFATTT
KRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPG
DWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLK
RLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELAD
TPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5xfr Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5xfr Polycomb-like proteins link the PRC2 complex to CpG islands
Resolution2.25 Å
Binding residue
(original residue number in PDB)		C122 C125 C154
Binding residue
(residue number reindexed from 1)		C69 C72 C94
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5xfr, PDBe:5xfr, PDBj:5xfr
PDBsum5xfr
PubMed28869966
UniProtQ9Y483|MTF2_HUMAN Metal-response element-binding transcription factor 2 (Gene Name=MTF2)

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