Structure of PDB 5luh Chain B Binding Site BS04

Receptor Information

>5luh Chain B (length=265) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLL
VTICQPLTEAQRATLMQELLALSSPPGASAEKRALQVTVVLYSQLVPWCF
PPSREMQFGEWLREDICQGIYEPAQQDWDMVLLITQILETSIPLKGERAE
RLFTPAPAAQLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGR
FTSKDAAADWLLPQLPEDYAATLRAAQREYLGLEQQDWHILLPAVVRFVD
FAKAHIPTQFTHHHH

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

5luh Chain B Residue 306 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5luh Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase fromSalmonella enterica.
Resolution	1.73 Å
Binding residue (original residue number in PDB)	D47 D49 Q87
Binding residue (residue number reindexed from 1)	D46 D48 Q86
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.7.7.47: streptomycin 3''-adenylyltransferase.

Gene Ontology

	Molecular Function
GO:0005524	ATP binding
GO:0009012	aminoglycoside 3''-adenylyltransferase activity
GO:0016779	nucleotidyltransferase activity
GO:0046872	metal ion binding
GO:0070566	adenylyltransferase activity

	Biological Process
GO:0046677	response to antibiotic

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Molecular Function

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Biological Process

External links

PDB	RCSB:5luh, PDBe:5luh, PDBj:5luh
PDBsum	5luh
PubMed	29871922
UniProt	Q8ZPX9\|S3AD_SALTY Aminoglycoside (3'') (9) adenylyltransferase (Gene Name=aadA)

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