Structure of PDB 5krb Chain B Binding Site BS04

Receptor Information
>5krb Chain B (length=74) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRTCLICGDRATGLHYGIISCEGCKGFFKRSISNKRVYRCSRDKNCVMSR
KQRNRCQYCRLLKCLQMGMNRKAI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5krb Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5krb A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1).
Resolution2.101 Å
Binding residue
(original residue number in PDB)		C111 C117 C127 C130
Binding residue
(residue number reindexed from 1)		C40 C46 C56 C59
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5krb, PDBe:5krb, PDBj:5krb
PDBsum5krb
PubMed27984042
UniProtQ64249|NR6A1_MOUSE Nuclear receptor subfamily 6 group A member 1 (Gene Name=Nr6a1)

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