Structure of PDB 5hoo Chain B Binding Site BS04

Receptor Information
>5hoo Chain B (length=336) Species: 7226 (Drosophila mauritiana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQR
FKSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQA
VSNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRI
VTGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGV
IYYELLKPGETVNAARYQQQLINLNRALQRKRPRVIFLHDNAPSHTARAV
RDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSYESVKKW
LDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5hoo A bend, flip and trap mechanism for transposon integration.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		A25 A26 R30 K44 E47 Q51 H65 K67 P68 K70 R71 V98 S99 Q101 R106 P174 G175 R183 R186 F187 T213 V214 N215 A216 P252 A256 R257
Binding residue
(residue number reindexed from 1)		A23 A24 R28 K42 E45 Q49 H63 K65 P66 K68 R69 V96 S97 Q99 R104 P172 G173 R181 R184 F185 T211 V212 N213 A214 P243 A247 R248
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0004519 endonuclease activity
GO:0042800 histone H3K4 methyltransferase activity
GO:0044547 DNA topoisomerase binding
GO:0046872 metal ion binding
GO:0046975 histone H3K36 methyltransferase activity
Biological Process
GO:0000729 DNA double-strand break processing
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006310 DNA recombination
GO:0006338 chromatin remodeling
GO:0015074 DNA integration
GO:0031297 replication fork processing
GO:0044774 mitotic DNA integrity checkpoint signaling
Cellular Component
GO:0000793 condensed chromosome
GO:0005634 nucleus
GO:0035861 site of double-strand break

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5hoo, PDBe:5hoo, PDBj:5hoo
PDBsum5hoo
PubMed27223327
UniProtQ7JQ07|MOS1T_DROMA Mariner Mos1 transposase (Gene Name=mariner\T)

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